Could be a bad tire. I bought brand new Michelins for my dually and had discount rebalance them 3 times because of an 80mph vibration that would shake the crap out of the truck. I finally forced them to do a "Road Force" balance (even though they said the RF wouldn't work on such a heavy tire) and they found I had a bad tire. They replaced the tire and all is good.
Anyway...inspect your wheels for signs that a wheel weight (particularly a large one) has come off. Look for uneven tire wear.
While you're at it. sping the drive shaft around and see if it looks like the balance weight on it has come off.