My uncle has an 05 SRW Ram 3500 4X4 with clod air intake, and dual turbo back 4" MBRP exhaust with no cat and 35" tires. At 55, which is the speed his truck get the best MPG at, he get about 20-22 on the highway.
hell at that speed, assuming i would still be alive, i get 21mpg too.