if ford told me right 4:88 is the standard gear in all f550's. i'm also looking into a gear change for my 550. the mileage is bad at what i figured out to be 6.5mpg.
My buddy put a US Gear in his dodge and he loves the thing. Said he gets like 22mpg with his 5th in tow and 28mpg just truck. It's a cool set up. He has a bumper sticker that says I have a 11 gears so shut up and drive!