There has been much discussion and misinformation about algae in diesel fuel. Algae require sunlight to live and grow. As there is no sunlight in a closed fuel tank, no algae can survive there. However, some microbes can survive there, and can feed on the diesel fuel.
These microbes form a slimy colony that lives at the fuel/water interface. They grow quite rapidly in warmer temperatures. They can even grow in cold weather when fuel tank heaters are installed. Parts of the colony can break off and clog the fuel lines and fuel filters.
It is possible to either kill this growth with a biocide treatment, or eliminate the water, a necessary component of microbial life. There are a number of biocides on the market, which must be handled very carefully. If a biocide is used, it must be added every time a tank is refilled until the problem is fully resolved.
Biocides attack the cell wall of microbes resulting in lysis, the death of a cell by bursting. The dead cells then gather on the bottom of the fuel tanks and form a sludge, filter clogging will continue after biocide treatment until the sludge has abated.
Given the right conditions microbes will repopulate the tanks and re-treatment with biocides will then be necessary. With repetitive biocide treatments microbes can then form resistance to a particular brand. Trying another brand may resolve this.